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Next generation molecular diagnostics platform

Next generation molecular diagnostics platformNext generation molecular diagnostics platformNext generation molecular diagnostics platform

Powered by engineered molecular motors, our technology revolutionizes quantitative home and point-of-care disease detection

Next generation molecular diagnostics platform

Next generation molecular diagnostics platformNext generation molecular diagnostics platformNext generation molecular diagnostics platform

Powered by engineered molecular motors, our technology revolutionizes quantitative home and point-of-care disease detection

SHARP Technology

SHARP is the next generation tool and platform for isothermal and low-temperature detection, amplification, and quantification of nucleic acids and modified variants. SHARP technology enables highly sensitive PCR molecular diagnostics without thermocyclers and exposure of biomolecules to high temperatures.

more about SHARP technology

Enzymatic isothermal amplification of nucleic acids

Innovative bioengineered motor proteins enable SHARP

SHARP method is powered by a novel bioengineered PcrA-M6 helicase motor protein to split the DNA duplex at constant temperature, while the conventional PCR requires a thermocycler to periodically heat the DNA above 95°C.  SHARP performs equally well or better than the conventional PCR in terms of the sensitivity, specificity and speed. SHARP enables next-generation robust and portable point-of-care molecular tests for human disease detection and monitoring, including HIV, HCV, TB, Covid-19, Influenza etc.

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